|
What is CIPRO XR?
CIPRO XR, an extended-release version of CIPRO® (ciprofloxacin), inhibits two enzymes
that bacteria need in order to multiply. Eventually, the bacteria die.
(For more information on CIPRO XR, please visit www.ciproxr.com.)
CIPRO XR pills come in two dosages:
The CIPRO XR pill containing 500 milligrams (mg) of the antibiotic ciprofloxacin, prescribed for uncomplicated urinary tract infections, is usually taken once a day for 3 days.
The CIPRO XR pill containing 1000 mg of the antibiotic, prescribed for complicated urinary tract infections and uncomplicated kidney infections, is usually taken once a day for 7 to 14 days.
Your healthcare professional will tell you how much CIPRO XR to take and for how long.
Because the concentration of CIPRO XR in the bladder is very high, it kills bacteria there quickly. CIPRO XR is especially powerful against the kinds of bacteria that typically cause urinary tract infections.
How and when should I take CIPRO XR?
CIPRO XR should be taken once a day for three (3) to fourteen (14) days depending on your infection. Take CIPRO XR at approximately the same time each day with food or on an empty stomach.
CIPRO XR should not be taken with dairy products (like milk or yogurt) or calcium-fortified juices alone; however, CIPRO XR may be taken with a meal that contains these products. Should you forget to take it at the usual time, you may take your dose later in the day. Do not take more than one CIPRO XR tablet per day even if you missed a dose. Swallow the CIPRO XR tablet whole. DO NOT SPLIT, CRUSH, OR CHEW THE TABLET.
You should take CIPRO XR for as long as your healthcare professional prescribes it, even after you start to feel better. Stopping an antibiotic too early may result in failure to cure your infection.
Who should not take CIPRO XR?
You should not take CIPRO XR if you have ever had a severe reaction to any of the group of antibiotics known as "quinolones."
CIPRO XR is not recommended for use during pregnancy or nursing, as the effects on the unborn child or nursing infant are unknown. If you are pregnant or plan to become pregnant while taking CIPRO XR, talk to your healthcare professional before taking this medication.
CIPRO XR is not recommended for persons less than 18 years of age.
What are the possible side effects of CIPRO XR?
CIPRO XR is generally well tolerated. The most common side effects, which are usually mild, include nausea, headache, dyspepsia, dizziness, vaginal yeast infection and diarrhea. If diarrhea persists, call your healthcare professional. Antibiotics of the quinolone class may also cause vomiting, rash, and abdominal pain/discomfort.
You should be careful about driving or operating machinery until you are sure CIPRO XR is not causing dizziness.
Rare cases of allergic reactions have been reported in patients receiving quinolones, including ciprofloxacin, even after just one dose. If you develop hives, difficulty breathing, or other symptoms of a severe allergic reaction, seek emergency treatment right away. If you develop a skin rash, you should stop taking CIPRO XR and call your healthcare professional.
Some patients taking quinolone antibiotics may become more sensitive to sunlight or ultraviolet light such as that used in tanning salons. You should avoid excessive exposure to sunlight or ultraviolet light while you are taking CIPRO XR.
Ciprofloxacin has been rarely associated with inflammation of tendons. If you experience pain, swelling or rupture of a tendon, you should stop taking CIPRO XR and call your healthcare professional.
Convulsions have been reported in patients receiving quinolone antibiotics including ciprofloxacin. If you have experienced convulsions in the past, be sure to let your physician know that you have a history of convulsions. Quinolones, including ciprofloxacin, have been rarely associated with other central nervous system events including confusion, tremors, hallucinations, and depression.
If you notice any side effects not mentioned in this section, or if you have any concerns about side effects you may be experiencing, please inform your healthcare professional.
What about other medications I am taking?
CIPRO XR can affect how other medicines work. Tell your healthcare professional about all other prescriptions and non-prescription medicines or supplements you are taking. This is especially important if you are taking theophylline or VIDEXÒ (didanosine) chewable/buffered tablets or pediatric powder. Other medications including warfarin, glyburide, and phenytoin may also interact with CIPRO XR.
Many antacids, multivitamins, and other dietary supplements containing magnesium, calcium, aluminum, iron or zinc can interfere with the absorption of CIPRO XR and may prevent it from working. You should take CIPRO XR either 2 hours before or 6 hours after taking these products.
Preventing bacterial resistance
Bacterial resistance to an antibiotic may develop if the bacteria are living in the presence of low concentrations of the antibiotic. So one way of preventing bacterial resistance is to take the recommended dose for the recommended time and to be careful about not missing doses. Overuse of an antibiotic—for example, taking the antibiotic often or taking it for a long time—may also contribute to the development of resistance.
Resistance is more common in some parts of the world than others. In some parts of the United States, up to one in five urinary tract infections may be caused by bacteria that are resistant to ordinary antibiotics like TMP/SMX. People living in those regions who develop a urinary tract infection can take a different antibiotic, such as CIPRO XR.
CIPRO has a long-established record of safety and effectiveness for a wide range of infections, including urinary tract infections.
Warning: Pregnant women, women who are breast-feeding, and anyone under age 18 should not take CIPRO XR or any other drug that contains ciprofloxacin.
How to get CIPRO XR
CIPRO XR and CIPRO are sold only by prescription.
Important Safety Information
Serious and fatal reactions have been reported in patients receiving concurrent administration of ciprofloxacin and theophylline. Monitor theophylline levels if concurrent administration cannot be avoided.
The safety and effectiveness of CIPRO XR in children, adolescents less than 18 years of age, pregnant women and lactating women have not been established. CIPRO XR is contraindicated in persons with a history of hypersensitivity to ciprofloxacin or any quinolone, and should be discontinued at the first sign of an allergic reaction.
Adverse reactions determined to be at least possibly drug-related occurring in greater than or equal to 1% of patients were nausea (3%), diarrhea (2%), headache (1%), dyspepsia (1%), dizziness (1%), and vaginal moniliasis (1%). Vomiting (1%) occurred in the 1000 mg dose.
CIPRO XR should be administered at least 2 hours before or 6 hours after antacids containing magnesium, aluminium, or other products containing metal cations. A 2-hour window between substantial calcium intake (>800 mg) and dosing with CIPRO XR is recommended.
DO NOT SPLIT, CRUSH, OR CHEW THE TABLET.
View Prescribing Information.
| 
